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SecA Cotranslationally Interacts with Nascent Substrate Proteins In Vivo

SecA is an essential component of the Sec machinery in bacteria, which is responsible for transporting proteins across the cytoplasmic membrane. Recent work from our laboratory indicates that SecA binds to ribosomes. Here, we used two different approaches to demonstrate that SecA also interacts with...

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Detalles Bibliográficos
Autores principales: Huber, Damon, Jamshad, Mohammed, Hanmer, Ruby, Schibich, Daniela, Döring, Kristina, Marcomini, Isabella, Kramer, Günter, Bukau, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198489/
https://www.ncbi.nlm.nih.gov/pubmed/27795329
http://dx.doi.org/10.1128/JB.00622-16