Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition

BACKGROUND: The nucleocapsid (NC) domain of HIV-1 Gag is responsible for specific recognition and packaging of genomic RNA (gRNA) into new viral particles. This occurs through specific interactions between the Gag NC domain and the Psi packaging signal in gRNA. In addition to this critical function,...

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Detalles Bibliográficos
Autores principales: Post, Klara, Olson, Erik D., Naufer, M. Nabuan, Gorelick, Robert J., Rouzina, Ioulia, Williams, Mark C., Musier-Forsyth, Karin, Levin, Judith G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198506/
https://www.ncbi.nlm.nih.gov/pubmed/28034301
http://dx.doi.org/10.1186/s12977-016-0322-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198506/
https://www.ncbi.nlm.nih.gov/pubmed/28034301
http://dx.doi.org/10.1186/s12977-016-0322-5

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