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Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition
BACKGROUND: The nucleocapsid (NC) domain of HIV-1 Gag is responsible for specific recognition and packaging of genomic RNA (gRNA) into new viral particles. This occurs through specific interactions between the Gag NC domain and the Psi packaging signal in gRNA. In addition to this critical function,...
Autores principales: | Post, Klara, Olson, Erik D., Naufer, M. Nabuan, Gorelick, Robert J., Rouzina, Ioulia, Williams, Mark C., Musier-Forsyth, Karin, Levin, Judith G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198506/ https://www.ncbi.nlm.nih.gov/pubmed/28034301 http://dx.doi.org/10.1186/s12977-016-0322-5 |
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