RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints

MOTIVATION: Deep sequencing based ribosome footprint profiling can provide novel insights into the regulatory mechanisms of protein translation. However, the observed ribosome profile is fundamentally confounded by transcriptional activity. In order to decipher principles of translation regulation,...

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Detalles Bibliográficos
Autores principales: Zhong, Yi, Karaletsos, Theofanis, Drewe, Philipp, Sreedharan, Vipin T, Kuo, David, Singh, Kamini, Wendel, Hans-Guido, Rätsch, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198522/
https://www.ncbi.nlm.nih.gov/pubmed/27634950
http://dx.doi.org/10.1093/bioinformatics/btw585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198522/
https://www.ncbi.nlm.nih.gov/pubmed/27634950
http://dx.doi.org/10.1093/bioinformatics/btw585

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