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Aspects of Weak Interactions between Folate and Glycine Betaine

[Image: see text] Folate, or vitamin B(9), is an important compound in one-carbon metabolism. Previous studies have found weaker binding of dihydrofolate to dihydrofolate reductase in the presence of osmolytes. In other words, osmolytes are more difficult to remove from the dihydrofolate solvation s...

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Detalles Bibliográficos
Autores principales: Bhojane, Purva P., Duff, Michael R., Bafna, Khushboo, Rimmer, Gabriella P., Agarwal, Pratul K., Howell, Elizabeth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198541/
https://www.ncbi.nlm.nih.gov/pubmed/27768285
http://dx.doi.org/10.1021/acs.biochem.6b00873