Yeast Reporter Assay to Identify Cellular Components of Ricin Toxin A Chain Trafficking

RTA, the catalytic A-subunit of the ribosome inactivating A/B toxin ricin, inhibits eukaryotic protein biosynthesis by depurination of 28S rRNA. Although cell surface binding of ricin holotoxin is mainly mediated through its B-subunit (RTB), sole application of RTA is also toxic, albeit to a signifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Becker, Björn, Schnöder, Tina, Schmitt, Manfred J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198560/
https://www.ncbi.nlm.nih.gov/pubmed/27929418
http://dx.doi.org/10.3390/toxins8120366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198560/
https://www.ncbi.nlm.nih.gov/pubmed/27929418
http://dx.doi.org/10.3390/toxins8120366

Ejemplares similares