Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis

Artesunate, an anti-malarial drug, has been repurposed as an anticancer drug due to its induction of cell death via reactive oxygen species (ROS) production. However, the molecular mechanisms regulating cancer cell death and the resistance of cells to artesunate remain unclear. We investigated the m...

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Detalles Bibliográficos
Autores principales: Roh, Jong-Lyel, Kim, Eun Hye, Jang, Hyejin, Shin, Daiha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198738/
https://www.ncbi.nlm.nih.gov/pubmed/28012440
http://dx.doi.org/10.1016/j.redox.2016.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198738/
https://www.ncbi.nlm.nih.gov/pubmed/28012440
http://dx.doi.org/10.1016/j.redox.2016.12.010

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