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Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearance

The NOD-like receptor pyrin domain 3 (NLRP3) inflammasome contains Nod-like receptors, a subclass of pattern recognition receptors, suggesting that this complex has a prominent role in host defenses. Various structurally diverse stimulators activate the NLRP3 inflammasome through different signaling...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Yu, Yang, Chuan-Hui, Tsai, Yung-Fong, Liaw, Chih-Chuang, Chang, Wen-Yi, Hwang, Tsong-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198739/
https://www.ncbi.nlm.nih.gov/pubmed/28012441
http://dx.doi.org/10.1016/j.redox.2016.12.018