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Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles

Oxidative stress, mainly contributed by reactive oxygen species (ROS), has been implicated in pathogenesis of several diseases. We review two primary examples; fibrosis and cancer. In fibrosis, ROS promote activation and proliferation of fibroblasts and myofibroblasts, activating TGF-β pathway in an...

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Detalles Bibliográficos
Autores principales: Morry, Jingga, Ngamcherdtrakul, Worapol, Yantasee, Wassana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198743/
https://www.ncbi.nlm.nih.gov/pubmed/28012439
http://dx.doi.org/10.1016/j.redox.2016.12.011