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Shakuyakukanzoto attenuates oxaliplatin-induced cold dysesthesia by inhibiting the expression of transient receptor potential melastatin 8 in mice

Oxaliplatin-induced peripheral neuropathy characterized especially as cold dysesthesia is a major dose-limiting side effect of the drug and is very difficult to control. In the present study, we examined whether the traditional herbal formulation Shakuyakukanzoto (SKT: 芍藥甘草湯Sháo Yào Gān Cǎo Tāng) co...

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Detalles Bibliográficos
Autores principales: Andoh, Tsugunobu, Mizoguchi, Shizuka, Kuraishi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198822/
https://www.ncbi.nlm.nih.gov/pubmed/28053885
http://dx.doi.org/10.1016/j.jtcme.2016.01.003