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The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism

INTRODUCTION: We analyzed the effects of the top 20 Alzheimer disease (AD) risk genes on gray-matter density (GMD) and metabolism. METHODS: We ran stepwise linear regression analysis using posterior cingulate hypometabolism and medial temporal GMD as outcomes and all risk variants as predictors whil...

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Detalles Bibliográficos
Autores principales: Stage, Eddie, Duran, Tugce, Risacher, Shannon L., Goukasian, Naira, Do, Triet M., West, John D., Wilhalme, Holly, Nho, Kwangsik, Phillips, Meredith, Elashoff, David, Saykin, Andrew J., Apostolova, Liana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198883/
https://www.ncbi.nlm.nih.gov/pubmed/28054028
http://dx.doi.org/10.1016/j.dadm.2016.12.003