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Synthesis of N-Mannich bases of berberine linking piperazine moieties revealing anticancer and antioxidant effects

A new Mannich base series of piperazine linked berberine analogues was furnished in this study to screen the antioxidant and anticancer potential of the resultant analogues. Alkoxy group at a C-9 position of berberine was converted to hydroxyl functionality to enhance the ability of final scaffolds...

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Detalles Bibliográficos
Autores principales: Mistry, Bhupendra, Patel, Rahul V., Keum, Young-Soo, Kim, Doo Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198934/
https://www.ncbi.nlm.nih.gov/pubmed/28053569
http://dx.doi.org/10.1016/j.sjbs.2015.09.005