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Synthesis of N-Mannich bases of berberine linking piperazine moieties revealing anticancer and antioxidant effects
A new Mannich base series of piperazine linked berberine analogues was furnished in this study to screen the antioxidant and anticancer potential of the resultant analogues. Alkoxy group at a C-9 position of berberine was converted to hydroxyl functionality to enhance the ability of final scaffolds...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198934/ https://www.ncbi.nlm.nih.gov/pubmed/28053569 http://dx.doi.org/10.1016/j.sjbs.2015.09.005 |