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EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway
The Ewing sarcoma breakpoint region 1 (EWSR1) gene is known to fuse with various partner genes to promote the development of the Ewing sarcoma family of tumors and other sarcomas. In contrast, the association of EWSR1 chimeric fusion genes with leukemia has rarely been reported. We identified a nove...
Autores principales: | Endo, Akifumi, Tomizawa, Daisuke, Aoki, Yuki, Morio, Tomohiro, Mizutani, Shuki, Takagi, Masatoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198945/ https://www.ncbi.nlm.nih.gov/pubmed/27627705 http://dx.doi.org/10.1111/cas.13080 |
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