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Zebularine enhances apoptosis of human osteosarcoma cells by suppressing methylation of ARHI

ARHI is an imprinted tumor suppressor gene and its methylation suppresses ARHI transcription levels to cause the development and progression of malignant tumors. Zebularine exerts a demethylation function for tumor suppressor genes. Our study aims to investigate the effect and mechanism of action of...

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Detalles Bibliográficos
Autores principales: Ye, Kaishan, Wang, Shuanke, Wang, Jing, Han, Hua, Ma, Bing, Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198947/
https://www.ncbi.nlm.nih.gov/pubmed/27685841
http://dx.doi.org/10.1111/cas.13088