Effect of AKT3 expression on MYC‐ and caspase‐8‐dependent apoptosis caused by polo‐like kinase inhibitors in HCT 116 cells

Polo‐like kinase (PLK) is a cell‐cycle regulator that is overexpressed in several cancer cell types. Polo‐like kinase is considered a novel target for cancer therapies, and several PLK inhibitors (PLKis), including BI 2536, BI 6727, and GSK461364, have been developed. In this study, we established f...

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Detalles Bibliográficos
Autores principales: Nonomiya, Yuma, Noguchi, Kohji, Tanaka, Noritaka, Kasagaki, Takahiro, Katayama, Kazuhiro, Sugimoto, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198950/
https://www.ncbi.nlm.nih.gov/pubmed/27699933
http://dx.doi.org/10.1111/cas.13093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198950/
https://www.ncbi.nlm.nih.gov/pubmed/27699933
http://dx.doi.org/10.1111/cas.13093

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