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LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1

BACKGROUND: Accumulating evidence supports the hypothesis that cancer stem cells (CSCs) are essential for cancer initiation, metastasis and drug resistance. However, the functional association of gastric CSC markers with stemness and epithelial-mesenchymal transition (EMT) signature genes is unclear...

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Detalles Bibliográficos
Autores principales: Wang, Bei, Chen, Queting, Cao, Yang, Ma, Xia, Yin, Chenxing, Jia, Youchao, Zang, Aimin, Fan, Wufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199039/
https://www.ncbi.nlm.nih.gov/pubmed/28033430
http://dx.doi.org/10.1371/journal.pone.0168904