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A Model Based Cost-Effectiveness Analysis of Routine Genotyping for CYP2D6 among Older, Depressed Inpatients Starting Nortriptyline Pharmacotherapy

OBJECTIVE: Genotyping for CYP2D6 has the potential to predict differences in metabolism of nortriptyline. This information could optimize pharmacotherapy. We determined the costs and effects of routine genotyping for old aged Dutch depressed inpatients. METHODS: With a decision-tree, we modelled the...

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Detalles Bibliográficos
Autores principales: Berm, Elizabeth J. J., Gout-Zwart, Judith J., Luttjeboer, Jos, Wilffert, Bob, Postma, Maarten J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199075/
https://www.ncbi.nlm.nih.gov/pubmed/28033366
http://dx.doi.org/10.1371/journal.pone.0169065