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The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing

In recent years, various large-scale proteomic studies have demonstrated that mitochondrial proteins are highly acylated, most commonly by addition of acetyl and succinyl groups. These acyl modifications may be enzyme catalysed but can also be driven non-enzymatically. The latter mechanism is promot...

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Detalles Bibliográficos
Autores principales: Hong, Shin Yee, Ng, Li Theng, Ng, Li Fang, Inoue, Takao, Tolwinski, Nicholas S., Hagen, Thilo, Gruber, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199114/
https://www.ncbi.nlm.nih.gov/pubmed/28033361
http://dx.doi.org/10.1371/journal.pone.0168752