Exploiting native forces to capture chromosome conformation in mammalian cell nuclei

Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understanding of this structure‐to‐function relationship. However, a...

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Detalles Bibliográficos
Autores principales: Brant, Lilija, Georgomanolis, Theodore, Nikolic, Milos, Brackley, Chris A, Kolovos, Petros, van Ijcken, Wilfred, Grosveld, Frank G, Marenduzzo, Davide, Papantonis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199122/
https://www.ncbi.nlm.nih.gov/pubmed/27940490
http://dx.doi.org/10.15252/msb.20167311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199122/
https://www.ncbi.nlm.nih.gov/pubmed/27940490
http://dx.doi.org/10.15252/msb.20167311

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