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Oxidized epigallocatechin gallate inhibited lysozyme fibrillation more strongly than the native form

Epigallocatechin gallate (EGCG), the most abundant flavanoid in green tea, is currently being evaluated in the clinic due to its benefits in the treatment of amyloid disorders. Its anti-amyloidogenic effect has been attributed to direct interaction of the intact molecule with misfolded polypeptides....

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Detalles Bibliográficos
Autores principales: An, Ting-Ting, Feng, Shuang, Zeng, Cheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199191/
https://www.ncbi.nlm.nih.gov/pubmed/28038426
http://dx.doi.org/10.1016/j.redox.2016.12.016