Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell

Activation of hepatic stellate cells (HSCs) is a pivotal event in liver fibrosis, characterized by dramatic disappearance of lipid droplets (LDs). Although LD disappearance has long been considered one of the hallmarks of HSC activation, the underlying molecular mechanisms are largely unknown. In th...

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Detalles Bibliográficos
Autores principales: Zhang, Zili, Zhao, Shifeng, Yao, Zhen, Wang, Ling, Shao, Jiangjuan, Chen, Anping, Zhang, Feng, Zheng, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199192/
https://www.ncbi.nlm.nih.gov/pubmed/28038427
http://dx.doi.org/10.1016/j.redox.2016.12.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199192/
https://www.ncbi.nlm.nih.gov/pubmed/28038427
http://dx.doi.org/10.1016/j.redox.2016.12.021

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