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TACO produces robust multi-sample transcriptome assemblies from RNA-seq

Accurate transcript structure and abundance inference from RNA-Seq data is foundational for molecular discovery. Here we present TACO, a computational method to reconstruct a consensus transcriptome from multiple RNA-Seq datasets. TACO employs novel change-point detection to demarcate transcript sta...

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Detalles Bibliográficos
Autores principales: Niknafs, Yashar S., Pandian, Balaji, Iyer, Hariharan K., Chinnaiyan, Arul M., Iyer, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199618/
https://www.ncbi.nlm.nih.gov/pubmed/27869815
http://dx.doi.org/10.1038/nmeth.4078