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A LGG-derived protein promotes IgA production through up-regulation of APRIL expression in intestinal epithelial cells

p40, a Lactobacillus rhamnosus GG (LGG)-derived protein, transactivates epidermal growth factor receptor (EGFR) in intestinal epithelial cells, leading to amelioration of intestinal injury and inflammation. To elucidate mechanisms by which p40 regulates mucosal immunity to prevent inflammation, this...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Liu, Liping, Moore, Daniel J, Shen, Xi, Peek, Richard M., Acra, Sari A, Li, Hui, Ren, Xiubao, Polk, D Brent, Yan, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199635/
https://www.ncbi.nlm.nih.gov/pubmed/27353252
http://dx.doi.org/10.1038/mi.2016.57