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A LGG-derived protein promotes IgA production through up-regulation of APRIL expression in intestinal epithelial cells
p40, a Lactobacillus rhamnosus GG (LGG)-derived protein, transactivates epidermal growth factor receptor (EGFR) in intestinal epithelial cells, leading to amelioration of intestinal injury and inflammation. To elucidate mechanisms by which p40 regulates mucosal immunity to prevent inflammation, this...
Autores principales: | Wang, Yang, Liu, Liping, Moore, Daniel J, Shen, Xi, Peek, Richard M., Acra, Sari A, Li, Hui, Ren, Xiubao, Polk, D Brent, Yan, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199635/ https://www.ncbi.nlm.nih.gov/pubmed/27353252 http://dx.doi.org/10.1038/mi.2016.57 |
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