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ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation

In understanding the mechanisms of cholesterol in the pathogenesis of atherosclerosis, previous studies from other laboratories have demonstrated that cholesterol crystals (CC) induce scavenger receptor CD36 expression and NLRP3-mediated inflammasome formation. In elucidating the mechanisms by which...

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Detalles Bibliográficos
Autores principales: Kotla, Sivareddy, Singh, Nikhlesh K., Rao, Gadiparthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200884/
https://www.ncbi.nlm.nih.gov/pubmed/28040583
http://dx.doi.org/10.1016/j.redox.2016.12.005