Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in primary B-NHL samples, identifying high HDAC9 express...

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Detalles Bibliográficos
Autores principales: Gil, Veronica S., Bhagat, Govind, Howell, Louise, Zhang, Jiyuan, Kim, Chae H., Stengel, Sven, Vega, Francisco, Zelent, Arthur, Petrie, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200892/
https://www.ncbi.nlm.nih.gov/pubmed/27799148
http://dx.doi.org/10.1242/dmm.023366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200892/
https://www.ncbi.nlm.nih.gov/pubmed/27799148
http://dx.doi.org/10.1242/dmm.023366

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