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DRIMSeq: a Dirichlet-multinomial framework for multivariate count outcomes in genomics

There are many instances in genomics data analyses where measurements are made on a multivariate response. For example, alternative splicing can lead to multiple expressed isoforms from the same primary transcript. There are situations where differences (e.g. between normal and disease state) in the...

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Detalles Bibliográficos
Autores principales: Nowicka, Malgorzata, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200948/
https://www.ncbi.nlm.nih.gov/pubmed/28105305
http://dx.doi.org/10.12688/f1000research.8900.2