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Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes
Vinculin is a highly conserved protein involved in cell adhesion and mechanotransduction, and both gain and loss of its activity causes defective cell behaviour. Here, we examine how altering vinculin activity perturbs integrin function within the context of Drosophila development. Whereas loss of v...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201009/ https://www.ncbi.nlm.nih.gov/pubmed/27737911 http://dx.doi.org/10.1242/jcs.189878 |