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The role and regulation of Rab40b–Tks5 complex during invadopodia formation and cancer cell invasion

Invadopodia formation and extracellular matrix degradation are key events during cancer cell invasion, yet little is known about mechanisms mediating these processes. Here, we report that Rab40b plays a key role in mediating invadopodia function during breast cancer cell invasion. We also identify T...

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Detalles Bibliográficos
Autores principales: Jacob, Abitha, Linklater, Erik, Bayless, Brian A., Lyons, Traci, Prekeris, Rytis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201011/
https://www.ncbi.nlm.nih.gov/pubmed/27789576
http://dx.doi.org/10.1242/jcs.193904