SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation

Sirtuin 2 (SIRT2) is an NAD-dependent deacetylase known to regulate microtubule dynamics and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, neurodegenerative diseases and progeria. Here, we show that SIRT2 depletion or overexpression causes nuclear envelope reasse...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaufmann, Tanja, Kukolj, Eva, Brachner, Andreas, Beltzung, Etienne, Bruno, Melania, Kostrhon, Sebastian, Opravil, Susanne, Hudecz, Otto, Mechtler, Karl, Warren, Graham, Slade, Dea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201015/
https://www.ncbi.nlm.nih.gov/pubmed/27875273
http://dx.doi.org/10.1242/jcs.192633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201015/
https://www.ncbi.nlm.nih.gov/pubmed/27875273
http://dx.doi.org/10.1242/jcs.192633

Ejemplares similares