RHO binding to FAM65A regulates Golgi reorientation during cell migration

Directional cell migration involves reorientation of the secretory machinery. However, the molecular mechanisms that control this reorientation are not well characterised. Here, we identify a new Rho effector protein, named FAM65A, which binds to active RHOA, RHOB and RHOC. FAM65A links RHO proteins...

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Detalles Bibliográficos
Autores principales: Mardakheh, Faraz K., Self, Annette, Marshall, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201024/
https://www.ncbi.nlm.nih.gov/pubmed/27807006
http://dx.doi.org/10.1242/jcs.198614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201024/
https://www.ncbi.nlm.nih.gov/pubmed/27807006
http://dx.doi.org/10.1242/jcs.198614

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