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RHO binding to FAM65A regulates Golgi reorientation during cell migration
Directional cell migration involves reorientation of the secretory machinery. However, the molecular mechanisms that control this reorientation are not well characterised. Here, we identify a new Rho effector protein, named FAM65A, which binds to active RHOA, RHOB and RHOC. FAM65A links RHO proteins...
Autores principales: | Mardakheh, Faraz K., Self, Annette, Marshall, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201024/ https://www.ncbi.nlm.nih.gov/pubmed/27807006 http://dx.doi.org/10.1242/jcs.198614 |
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