Transient Activation of GABA(B) Receptors Suppresses SK Channel Currents in Substantia Nigra Pars Compacta Dopaminergic Neurons

Dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) are richly innervated by GABAergic neurons. The postsynaptic effects of GABA on SNc DA neurons are mediated by a mixture of GABA(A) and GABA(B) receptors. Although activation of GABA(A) receptors inhibits spike generation, the con...

Descripción completa

Detalles Bibliográficos
Autores principales: Estep, Chad M., Galtieri, Daniel J., Zampese, Enrico, Goldberg, Joshua A., Brichta, Lars, Greengard, Paul, Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201262/
https://www.ncbi.nlm.nih.gov/pubmed/28036359
http://dx.doi.org/10.1371/journal.pone.0169044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201262/
https://www.ncbi.nlm.nih.gov/pubmed/28036359
http://dx.doi.org/10.1371/journal.pone.0169044

Ejemplares similares