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Transient Activation of GABA(B) Receptors Suppresses SK Channel Currents in Substantia Nigra Pars Compacta Dopaminergic Neurons
Dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) are richly innervated by GABAergic neurons. The postsynaptic effects of GABA on SNc DA neurons are mediated by a mixture of GABA(A) and GABA(B) receptors. Although activation of GABA(A) receptors inhibits spike generation, the con...
Autores principales: | Estep, Chad M., Galtieri, Daniel J., Zampese, Enrico, Goldberg, Joshua A., Brichta, Lars, Greengard, Paul, Surmeier, D. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201262/ https://www.ncbi.nlm.nih.gov/pubmed/28036359 http://dx.doi.org/10.1371/journal.pone.0169044 |
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