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Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by the abnormal proteolytic processing of amyloid precursor protein, resulting in increased production of a self-aggregating form of beta amyloid (Aβ). Several lines of work on AD patients and transgenic mice with high Aβ levels exhibit altered rhythmicity,...

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Detalles Bibliográficos
Autores principales: Perez, Carlos, Ziburkus, Jokubas, Ullah, Ghanim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201300/
https://www.ncbi.nlm.nih.gov/pubmed/28036398
http://dx.doi.org/10.1371/journal.pone.0168800