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Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by the abnormal proteolytic processing of amyloid precursor protein, resulting in increased production of a self-aggregating form of beta amyloid (Aβ). Several lines of work on AD patients and transgenic mice with high Aβ levels exhibit altered rhythmicity,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201300/ https://www.ncbi.nlm.nih.gov/pubmed/28036398 http://dx.doi.org/10.1371/journal.pone.0168800 |