Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

BACKGROUND: Human embryonic stem cells (hESCs) partially recapitulate early embryonic three germ layer development, allowing testing of potential teratogenic hazards. Because use of hESCs is ethically debated, we investigated the potential for human induced pluripotent stem cells (hiPSCs) to replace...

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Detalles Bibliográficos
Autores principales: Shinde, Vaibhav, Perumal Srinivasan, Sureshkumar, Henry, Margit, Rotshteyn, Tamara, Hescheler, Jürgen, Rahnenführer, Jörg, Grinberg, Marianna, Meisig, Johannes, Blüthgen, Nils, Waldmann, Tanja, Leist, Marcel, Hengstler, Jan Georg, Sachinidis, Agapios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203708/
https://www.ncbi.nlm.nih.gov/pubmed/28038682
http://dx.doi.org/10.1186/s13287-016-0449-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203708/
https://www.ncbi.nlm.nih.gov/pubmed/28038682
http://dx.doi.org/10.1186/s13287-016-0449-2

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