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Human splicing diversity and the extent of unannotated splice junctions across human RNA-seq samples on the Sequence Read Archive
BACKGROUND: Gene annotations, such as those in GENCODE, are derived primarily from alignments of spliced cDNA sequences and protein sequences. The impact of RNA-seq data on annotation has been confined to major projects like ENCODE and Illumina Body Map 2.0. RESULTS: We aligned 21,504 Illumina-seque...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203714/ https://www.ncbi.nlm.nih.gov/pubmed/28038678 http://dx.doi.org/10.1186/s13059-016-1118-6 |