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Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model

BACKGROUND: Current data on antidepressant action of the N-methyl-D-aspartate receptor antagonist, (+)-MK-801, is inconsistent. This study was conducted to examine the effects of (+)-MK-801 and its less potent stereoisomer, (-)-MK-801, in the social defeat stress model of depression. METHODS: The an...

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Detalles Bibliográficos
Autores principales: Yang, Bangkun, Ren, Qian, Ma, Min, Chen, Qian-Xue, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203762/
https://www.ncbi.nlm.nih.gov/pubmed/27608811
http://dx.doi.org/10.1093/ijnp/pyw080