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Serological and genetic complement alterations in infection-induced and complement-mediated hemolytic uremic syndrome

BACKGROUND: The role of complement in the atypical form of hemolytic uremic syndrome (aHUS) has been investigated extensively in recent years. As the HUS-associated bacteria Shiga-toxin-producing Escherichia coli (STEC) can evade the complement system, we hypothesized that complement dysregulation i...

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Detalles Bibliográficos
Autores principales: Westra, Dineke, Volokhina, Elena B., van der Molen, Renate G., van der Velden, Thea J. A. M., Jeronimus-Klaasen, Annelies, Goertz, Joop, Gracchi, Valentina, Dorresteijn, Eiske M., Bouts, Antonia H. M., Keijzer-Veen, Mandy G., van Wijk, Joanna A. E., Bakker, Jaap A., Roos, Anja, van den Heuvel, Lambert P., van de Kar, Nicole C. A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203860/
https://www.ncbi.nlm.nih.gov/pubmed/27718086
http://dx.doi.org/10.1007/s00467-016-3496-0