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Prenatal Dexamethasone Exposure Increases the Susceptibility to Autoimmunity in Offspring Rats by Epigenetic Programing of Glucocorticoid Receptor

Objective. Prenatal glucocorticoids (GC) can induce long term effects on offspring health. However, reports and related studies regarding the prolonged effects of prenatal GC on the development of autoimmunity are limited. Here, we aimed to explore the immunological effects of dexamethasone (DEX) ex...

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Detalles Bibliográficos
Autores principales: Sun, Yanhong, Wan, Xiaoyan, Ouyang, Juan, Xie, Renfeng, Wang, Xueping, Chen, Peisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203882/
https://www.ncbi.nlm.nih.gov/pubmed/28078304
http://dx.doi.org/10.1155/2016/9409452