Noncanonical IFN Signaling: Mechanistic Linkage of Genetic and Epigenetic Events

The canonical model of cytokine signaling via the JAK/STAT pathway dominates our view of signal transduction but provides no insight into the significance of the simultaneous presence of activated JAKs and STATs in the nucleus of cells treated with cytokines. Such a mechanistic shortcoming challenge...

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Detalles Bibliográficos
Autores principales: Johnson, Howard M., Ahmed, Chulbul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203919/
https://www.ncbi.nlm.nih.gov/pubmed/28077919
http://dx.doi.org/10.1155/2016/9564814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203919/
https://www.ncbi.nlm.nih.gov/pubmed/28077919
http://dx.doi.org/10.1155/2016/9564814

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