Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile

DNA replication is an essential and conserved process in all domains of life and may serve as a target for the development of new antimicrobials. However, such developments are hindered by subtle mechanistic differences and limited understanding of DNA replication in pathogenic microorganisms. Clost...

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Detalles Bibliográficos
Autores principales: van Eijk, Erika, Paschalis, Vasileios, Green, Matthew, Friggen, Annemieke H., Larson, Marilynn A., Spriggs, Keith, Briggs, Geoffrey S., Soultanas, Panos, Smits, Wiep Klaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204125/
https://www.ncbi.nlm.nih.gov/pubmed/28003473
http://dx.doi.org/10.1098/rsob.160272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204125/
https://www.ncbi.nlm.nih.gov/pubmed/28003473
http://dx.doi.org/10.1098/rsob.160272

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