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Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile
DNA replication is an essential and conserved process in all domains of life and may serve as a target for the development of new antimicrobials. However, such developments are hindered by subtle mechanistic differences and limited understanding of DNA replication in pathogenic microorganisms. Clost...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204125/ https://www.ncbi.nlm.nih.gov/pubmed/28003473 http://dx.doi.org/10.1098/rsob.160272 |