Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint

The spindle assembly checkpoint (SAC) maintains genomic integrity by preventing progression of mitotic cell division until all chromosomes are stably attached to spindle microtubules. The SAC critically relies on the paralogues Bub1 and BubR1/Mad3, which integrate kinetochore–spindle attachment stat...

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Detalles Bibliográficos
Autores principales: Tromer, Eelco, Bade, Debora, Snel, Berend, Kops, Geert J. P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204127/
https://www.ncbi.nlm.nih.gov/pubmed/28003474
http://dx.doi.org/10.1098/rsob.160315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204127/
https://www.ncbi.nlm.nih.gov/pubmed/28003474
http://dx.doi.org/10.1098/rsob.160315

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