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Mechanistic insights into acyclovir-polyethylene glycol 20000 binary dispersions

OBJECTIVE: The objective of this study is to provide a mechanistic insight into solubility enhancement and dissolution of acyclovir (ACY) by polyethylene glycol20000 (PEG20000). MATERIALS AND METHODS: Solid dispersions with differing ratios of drug (ACY) and carrier (PEG20000) were prepared and eval...

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Detalles Bibliográficos
Autores principales: Venkateskumar, Krishnamoorthy, Parasuraman, Subramani, Gunasunderi, Raju, Sureshkumar, Krishnan, Nayak, M. Muralidhar, Shah, Syed Adnan Ali, Kassen, Khoo, Kai, Heng Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204250/
https://www.ncbi.nlm.nih.gov/pubmed/28123988
http://dx.doi.org/10.4103/2230-973X.195925