Hepatocytes Are the Principal Source of Circulating RBP4 in Mice

RBP4 is produced mainly by hepatocytes. In type 2 diabetes and obesity, circulating RBP4 is increased and may act systemically to cause insulin resistance and glucose intolerance. Observations that adipocyte RBP4 mRNA increases in parallel with circulating RBP4 in these conditions, whereas liver RBP...

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Detalles Bibliográficos
Autores principales: Thompson, Spencer J., Sargsyan, Ashot, Lee, Seung-Ah, Yuen, Jason J., Cai, Jinjin, Smalling, Rana, Ghyselinck, Norbert, Mark, Manuel, Blaner, William S., Graham, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204311/
https://www.ncbi.nlm.nih.gov/pubmed/27797907
http://dx.doi.org/10.2337/db16-0286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204311/
https://www.ncbi.nlm.nih.gov/pubmed/27797907
http://dx.doi.org/10.2337/db16-0286

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