A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats

The pathogenesis of human type 1 diabetes, characterized by immune-mediated damage of insulin-producing β-cells of pancreatic islets, may involve viral infection. Essential components of the innate immune antiviral response, including type I interferon (IFN) and IFN receptor–mediated signaling pathw...

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Detalles Bibliográficos
Autores principales: Qaisar, Natasha, Lin, Suvana, Ryan, Glennice, Yang, Chaoxing, Oikemus, Sarah R., Brodsky, Michael H., Bortell, Rita, Mordes, John P., Wang, Jennifer P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204313/
https://www.ncbi.nlm.nih.gov/pubmed/27999109
http://dx.doi.org/10.2337/db16-0462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204313/
https://www.ncbi.nlm.nih.gov/pubmed/27999109
http://dx.doi.org/10.2337/db16-0462

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