The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells

Cancer cells exhibit multiple epigenetic changes with prominent local DNA hypermethylation and widespread hypomethylation affecting large chromosomal domains. Epigenome studies often disregard the study of repeat elements owing to technical complexity and their undefined role in genome regulation. W...

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Detalles Bibliográficos
Autores principales: Jordà, Mireia, Díez-Villanueva, Anna, Mallona, Izaskun, Martín, Berta, Lois, Sergi, Barrera, Víctor, Esteller, Manel, Vavouri, Tanya, Peinado, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204336/
https://www.ncbi.nlm.nih.gov/pubmed/27999094
http://dx.doi.org/10.1101/gr.207522.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204336/
https://www.ncbi.nlm.nih.gov/pubmed/27999094
http://dx.doi.org/10.1101/gr.207522.116

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