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The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells
Cancer cells exhibit multiple epigenetic changes with prominent local DNA hypermethylation and widespread hypomethylation affecting large chromosomal domains. Epigenome studies often disregard the study of repeat elements owing to technical complexity and their undefined role in genome regulation. W...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204336/ https://www.ncbi.nlm.nih.gov/pubmed/27999094 http://dx.doi.org/10.1101/gr.207522.116 |